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oncology differential behcet classification cll cold cvid gap globulin hodgkins hypogammaglobulinemia immunodeficiency immunology lymphocytic monoclonal paraproteinemias protein proteingap signs symptoms
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Syndrome (CAS): ... Diagnosis: • hemolytic ... , HIV, rubella legionella ... #disease #hemolytic ... #anemia #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Epidemiology: • Most common ... cells can indicate disease ... • Neutropenia, anemia ... #diagnosis #workup ... #oncology #hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
and autoimmune hemolytic ... anemia) • Systemic ... , HIV) • Glucocorticoid ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
anemia • Pain ... (NSHL) - (most common ... Workup: • Full ... #hematology #oncology ... #management
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
(HCV) • CLL & ... et diutinum Neurologic ... • Coombs (-) hemolytic ... anemia due to cold ... Paraproteinemias #Hematology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
of age • Most common ... skin injury) • Neurologic ... , Lymphoma Ocular ... #diagnosis #management ... signs #symptoms #rheumatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
infections (acute HIV ... , HBV, EBV, VZV, ... gastric tumors • Hematology ... : Lymphoma, Leukemia ... #hematology
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