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pulmonary amiodarone boop cancer cop cryptogenic ctchest differential hemophagocytic hlh hyponatremia induced interpretation lung lymphohistiocytosis nephrology oncology organizing pneumonia radiology
Cryptogenic Organizing Pneumonia (COP) Cryptogenic Organizing Pneumonia Overview: • Idiopathic form of organizing pneumonia • formerly BOOP
- Imaging: • CXR ... irregular lines, nodular ... , cavities • HRCT ... BOOP #pulmonary #ILD ... #diagnosis #management
Basic Interpretation A structured approach to interpretation of HRCT involves the following questions: What is the dominant HR-pattern: reticular nodular high
interpretation of HRCT ... HR-pattern: reticular nodular ... Radiology #Pulmonary #HRCT ... Interpretation #Algorithm ... #ILD #RadiologyAssistant
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
cytokines (TNFa,lL1, IL6 ... Auto-amplification loop Diagnosis ... PTLD), allogeneic HSCT ... #management #treatment ... #summary #rheumatology
Amiodarone Induced Lung Toxicity Summary Who? • 5% of patients • Dose ≥ 400 mg per day How? Possible
multiple pulmonary nodules ... • Reticular + Nodular ... Exclusion of other ILDs ... confirmatory findings on HRCT ... #management #Toxicology
Hyponatremia Differential Diagnosis Algorithm in Cancer UOsm ≥ 100 mOsm/kg = Urine is inappropriately concentrated for hypotonic
Hyponatremia Differential Diagnosis ... Algorithm in Cancer ... - and IL-2- induced ... VOD following HSCT ... #Cancer #algorithm
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