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Differential diagnosis on HRCT
Most of our knowledge about imaging findings in interstitial lung disease comes from
on HRCT Most of ... disease comes from HRCT ... On HRCT there are ... low attenuation (table ... #Pulmonary #CXR
Figure 3 HRCT-LUS correlation in normal lung, pulmonary congestion, rheumatoid lung disease, idiopathic pulmonary fibrosis.
Notes: (A)
Figure 3 HRCT-LUS ... #Clinical #Diagnosis ... #HRCT #POCUS #Lung ... #Correlation #Table ... #ILD #Findings
UIP
UIP is a histologic pattern of pulmonary fibrosis.
On a chest X-ray UIP manifests as a reticular
histologic pattern of pulmonary ... A HRCT is needed ... to confirm the diagnosis ... Here a CXR with ... HRCT demonstrated
Upper lung zone preference is seen in:
- Inhaled particles: pneumoconiosis (silica or coal)
- Smoking related diseases
bronchiolitis (RB-ILD ... edema #Diagnosis ... #Radiology #Pulmonary ... #HRCT #ChestCT ... #Differential #Table
The idiopathic interstitial pneumonias (IIPs) comprise a heterogenous group of disorders. 
They represent fundamental responses of
indicates unknown cause ... listed in the table ... on HRCT and histology ... #Diagnosis #Radiology ... #Pulmonary #CTChest
Basic Interpretation
A structured approach to interpretation of HRCT involves the following questions:
What is the dominant HR-pattern:
reticular
nodular
high
interpretation of HRCT ... dominant HR-pattern: reticular ... there additional findings ... #Radiology #Pulmonary ... #HRCT #CTChest
Reticular pattern 
1. Lymphangitic carcinomatosis: irregular septal thickening, usually focal or unilateral 50% adenopathy', known carcinoma.
2.
Reticular pattern ... edema: incidental finding ... in HRCT, smooth ... Clinical #Radiology #HRCT ... Pattern #Comparison #Table
Here are the most common examples of these four patterns on a chest x-ray (click image
Interstitial - Reticular ... mass - Solitary Pulmonary ... Nodule - Multiple Masses ... Atelectasis #Diagnosis ... Clinical #Radiology #CXR
Amiodarone Induced Lung Toxicity Summary

Who?
• 5% of patients
• Dose ≥ 400 mg per day

How?  Possible
Characteristic finding ... Exclude other causes ... Exclusion of other ILDs ... ground glass or reticular ... on HRCT is highly
Septal thickening
Thickening of the lung interstitium by fluid, fibrous tissue, or infiltration by cells results in
in a pattern of reticular ... a predominant finding ... (Table). ... #Pulmonary #HRCT ... #CTChest #Reticular