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Membrane Actions of Antiarrhythmic Drugs

#Membrane #Channels #Actions #Antiarrhythmic #Drugs #Medications #Pharmacology #Cardiology #Table
Membrane Actions ... of Antiarrhythmic ... #Channels #Actions ... #Pharmacology # ... Cardiology #Table
Drugs affecting the cardiac action potential. The sharp rise in voltage ("0") corresponds to the influx
Drugs affecting ... the cardiac action ... to the sodium-channel ... voltage-sensitive calcium channels ... #Cardiology #Antiarrhythmics
Antiarrhythmics - Sodium Channel Blockers
Subclasses, Mechanisms, Indications, Side Effects
la - Quinidine, Procainamide
lb - Lidocaine, Mexiletine
Ic -
- Sodium Channel ... Indications, Side Effects ... #Sodium #Channel ... #pharmacology # ... table #comparison
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
Antiarrhythmics ... CLASS 1 - Sodium Channel ... Block fast Na+ channels ... blocking effects ... Vaughan #Williams #Pharmacology
Calcium Channel Blockers - Dihydropyridines vs Non-Dihydropyridines
Dihydropyridines (amlodipine, felodipine, nifedipine, nicardipine)
 • SVR: Decrease
 • Inotropy:
Calcium Channel ... EricsMedicalLectures/ #CCBs ... #Calcium #Channel ... #comparison #table ... #cardiology
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Antiarrhythmics ... Pharmacology Summary ... blocking effects ... inotropy) ACCP Cardiology ... #Pharmacology #
Class III Antiarrhythmics - Potassium Channel Blockers - Indications and Side Effects
Amiodarone
 • Suppression of VT
- Potassium Channel ... Indications and Side Effects ... a-flutter (when other drugs ... #Potassium #Channel ... #cardiology
Clinically Significant Cardiovascular Drug-Drug Interactions With OTC Supplements and Herbal Products
Angiotensin-Converting Enzyme Inhibitors (ACEIs)
 • Night-blooming
Cardiovascular Drug-Drug ... tachycardia Calcium Channel ... arrhythmias Class I Antiarrhythmic ... supplementals #herbal #pharmacology ... #DDI #table #cardiology
Sedative-Hypnotic Drugs
Benzodiazepines:
 - Bind to specific GABAA receptor subunits at central nervous system (CNS) neuronal synapses
GABA-mediated chloride ion channel ... GABA-mediated chloride ion channel ... GABAA receptors, acting ... #medications #pharmacology ... #comparison #table