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management syndrome reactions treatment differential guillain product rheumatology transfusion alkaline alp associated cauda caudaequina centralretinalartery cerebritis coagulation comparison crao dementia
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
- Summary Acute ... AIDP that presents ... Pathophysiology ... Diagnosis: • ... management #treatment #neurology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
malignancy (Especially acute ... ABO incompatible blood ... Thromboembolism (7%) • CNS ... #Coagulation #diagnosis ... #management #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Disease, PRES Pathophysiology ... autoantibodies that will cause ... thrombosis and/or blood-brain ... #neurology #rheumatology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
of high parity blood ... without other cause ... At least 3 of (Acute ... Transfusion #Reactions #hematology ... #diagnosis #comparison
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
(GBS) Acute autoimmune ... Incidence: 1 to 2 cases ... normal CSF white blood ... the underlying pathophysiology ... #management #neurology
HIV-Associated Neurocognitive Disorder (HAND) Definition: HIV-Associated Neurocognitive disorders categories: • Asymptomatic neurocognitive impairment • Mild neurocognitive impairment • HIV dementia Pathophysiology: HIV frequently
dementia Pathophysiology ... and infects the CNS ... Diagnosis: MRI ... disorder #dementia #AIDS ... #Neurology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
involvement • 30%: CNS ... -> AML: Blast crises ... Fibrinolysis & DIC ... #Leukemia #Hematology ... #Oncology #Diagnosis
Central Retinal Artery Occlusion: Pathogenesis and clinical findings • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
anti-coagulation • Hematologic ... trucking" • Acute ... retinal edema caused ... Occlusion #CRAO #pathophysiology ... ophthalmology #diagnosis
Cauda Equina Syndrome Overview Cauda Equina Syndrome: • Prevalence: 1:33,000-100,000 ppl/yr • Incidence: 1.5-3.4 million ppl/yr •
spine • MCC- acute ... equina syndrome (CES ... - Emergency Causes ... cord • Guillain-Barre ... #causes #neurology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
• Acute Hemolytic ... pain, dark urine, DIC ... Transfusion Related Acute ... #Transfusion #diagnosis ... #management #hematology
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