7 results
Leg Pain - Differential Diagnosis Framework

Bone/Joint Causes of Leg Pain:
 • Fracture
 • Arthritis
 • Gout/pseudogout
: • Infection: ... Epidural abscess - Herpes ... zoster - HIV ... /swelling - Fever ... extremity #msk #physicalexam
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
to exclude are infections ... Large Vessel: Blood ... Cryoglobulins • HIV ... • HBV HCV • ... differential #diagnosis #rheumatology
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Approach to Joint Pain ... acute rheumatic fever ... - parvovirus, HIV ... , hepatitis, herpes ... #rheumatology #
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
pain, dark urine ... with skin flora ... Extremely rare - HIV ... 2,000,000,000, HBV ... in 100,000,000, HCV
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
pain, dark urine ... with skin flora ... Extremely rare - HIV ... 2,000,000,000, HBV ... in 100,000,000, HCV
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
negative anti-lgG ... Mycoplasma, EBV, HIV ... sensitize red blood ... Symptoms: High fevers ... chills, flank pain
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
pulses, bruits, or blood ... arthralgia, arm/leg ... tract: Abdominal pain ... HTN • Check: HBV ... Differential #Diagnosis #Rheumatology