11 results
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
TB: • HIV • Recent ... are pulmonary • HIV ... Treatment: Active ... TST or IGRA HIV ... : • HIV-infected
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
TB: • HIV • Recent ... are pulmonary • HIV ... Treatment: Active ... TST or IGRA HIV ... : • HIV-infected
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
in HIV - Differential ... macrophages in HIV ... low if you have HIV ... nodules possible in HIV ... #Infections #HIV
Tuberculin Skin Test Interpretation - Threshold for treatment
Induration cutoff >5mm:
 • Recent exposure to an individual
Threshold for treatment ... individual with active ... disease • HIV ... carcinoma of head/neck/lung ... individuals #Tuberculosis
Cryptogenic Organizing Pneumonia (COP)

Cryptogenic Organizing Pneumonia Overview:
 • Idiopathic form of organizing pneumonia
 • formerly BOOP
of interstitial lung ... - Clinical manifestations ... legionella/strep, HIV ... Anti-dsDNA, ANCA COP DDX ... Treatment: •
IDSA Recommendations for Treating Mycobacterium Tuberculosis Infection and Disease in HIV-AIDS
Treating LTBI (to prevent TB disease)
Indications:
and Disease in HIV-AIDS ... be initiated in HIV-infected ... persons with clinical ... suggestive of HIV-related ... for HIV-related
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
of HIV/AIDS patients ... • 10-20% of HIV-infected ... a decrease in HIV ... pancreatitis • HBV ... , HCV - Hepatic
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... • Chronic lung ... community-acquired infections: Pneumonia ... DDX - Other causes ... , HIV) • Glucocorticoid
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Mycobacterium tuberculosis ... : • Syndrome of ... mucogenicum • HIV ... Kansasii: • Mimics TB ... Advanced HIV (CD4
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Can cause TYPE IV ... salivary ducts Clinical ... MALT Lymphoma • Lung ... Adenocarcinoma Treatment ... muscarinic agonists • Active