7 results
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Active TB: • HIV ... disease • DM DDX ... are pulmonary • HIV ... TST or IGRA HIV ... : • HIV-infected
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Active TB: • HIV ... disease • DM DDX ... are pulmonary • HIV ... TST or IGRA HIV ... : • HIV-infected
Cryptogenic Organizing Pneumonia (COP)

Cryptogenic Organizing Pneumonia Overview:
 • Idiopathic form of organizing pneumonia
 • formerly BOOP
of interstitial lung ... Organizing Pneumonia - Clinical ... legionella/strep, HIV ... Anti-dsDNA, ANCA COP DDX ... Organizing Pneumonia Treatment
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan
Beta-D-Glucan:
 • Polysaccharide cell wall component of many fungi
 • Pathogens:
cut-offs defined in clinical ... BAL GM does not differentiate ... Clav (may be + as long ... setting of GVHD) ID ... Fungal #Biomarkers #BetaDGlucan
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives
1,3-Beta-D-Glucan
 • Cell wall component of many fungi
positives: IVIG, IV ... Spec 81% for dx ... in BAL does not differentiate ... result in + as long ... blood products #BetaDGlucan
Endocarditis - Overview and Differential Diagnosis Framework

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV
- Overview and Differential ... , verrucous) - Lung ... Glomerulonephritis DDX ... hematuria, + RF Treatment ... #Endocarditis #Differential
Cryptococcal meningitis on T2 MRI
30 M from sub-Saharan Africa presents w/ progressive Headache x1 mo, +neck
Cryptococcal meningitis, hiv ... DDX Tb meningitis ... sign on mri) HIV-infected ... Standard treatment ... #radiology