12 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Risks factor for HIV ... , HCV - Alcohol ... peripheral blood smear, HIV ... /HCV testing - ... #Workup #hematology
Kaposis Sarcoma: Darkly pigmented macules caused by this malignancy. Seen most commonly in
patients with HIV infection.

Charlie
pigmented macules caused ... patients with HIV ... infection. ... Images #Clinical ... #Photo #Dermatology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Avg age of DX ... to 8 years Clinical ... DDX - Other causes ... Epstein-Barr syndrome, HIV ... hypogammaglobulinemia #immunology #hematology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Syndrome: • Clinical ... : HCV infection, ... HBV infection, ... HIV infection ... DDX: • ANCA (Antineutrophil
Vibrio Vulnificus skin infection
Cirrhosis w/recent consumption of raw oysters w/rapidly evolving rash. 
Vibrio vulnificus part of
Vulnificus skin infection ... marine microbiota & causes ... hemolytic anemia, CKD, hiv ... rash #cellulitis #dermatology ... #legs #clinical
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
- CMV - HCV ... - HIV • Immune ... and thymoma DDX ... immunodeficiency virus (HIV ... Anemia #oncology #hematology
Capnocytophaga Canimorsus Skin Rash

40 M presents w/ N, V, severe epigastric pain. SHx: smoker, drinks 18
with wife, bit by his ... Dx? ... dogs & latter can cause ... Canimorsus #Skin #Rash #dermatology ... #clinical #photo
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Malignancy • Infections ... cryoglobulins • Negative causes ... Cryofibrinogenemia DDX ... • TTP, HUS and HIT ... #hematology
Cutaneous Mucormycosis Eschar
30 M HIV cd4 10 VL 30k traumatic injury of arm few months ago
Mucormycosis Eschar 30 M HIV ... malnutrition, HIV ... & steroid use Dx ... Mucormycosis #Eschar #dermatology ... #skin #clinical
Rickettsialpox Eschar

40 homeless male from NY admitted with fever, chills, headache, myalgias. Diagnosis?
Rickettsialpox R akari classic
other rickettsia) Dx ... : serology; pcr ... , hsv, Queensland ... Eschar #rakari #clinical ... photo #skinrash #dermatology