10 results
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Clinical Presentation ... - CMV - HCV ... - HIV • Immune ... and thymoma DDX ... immunodeficiency virus (HIV
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
procedures - Infection ... Risks factor for HIV ... , HCV - Alcohol ... peripheral blood smear, HIV ... /HCV testing -
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Avg age of DX ... to 8 years Clinical ... autoimmune hemolytic anemia ... DDX - Other causes ... Epstein-Barr syndrome, HIV
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Syndrome: • Clinical ... : HCV infection, ... HBV infection, ... HIV infection ... classification #rheumatology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Clinical Presentation ... • Symptoms of anemia ... • hemolytic anemia ... Mycoplasma, EBV, HIV ... #hematology #diagnosis
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... the presence of anemia ... Additional tests: HIV ... ANA and RF (if clinical ... diagnosis #testing #Rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
affects the skin, neurologic ... HTN • Check: HBV ... cognitive impairment, neurologic ... drug exposure or Dx ... Differential #Diagnosis #Rheumatology
Cutaneous Mucormycosis Eschar
30 M HIV cd4 10 VL 30k traumatic injury of arm few months ago
Mucormycosis Eschar 30 M HIV ... malnutrition, HIV ... trauma, aplastic anemia ... & steroid use Dx ... dermatology #skin #clinical
Rickettsialpox Eschar

40 homeless male from NY admitted with fever, chills, headache, myalgias. Diagnosis?
Rickettsialpox R akari classic
other rickettsia) Dx ... : serology; pcr ... , hsv, Queensland ... Indiana University Infectious ... Eschar #rakari #clinical
Cryptococcal meningitis on T2 MRI
30 M from sub-Saharan Africa presents w/ progressive Headache x1 mo, +neck
Cryptococcal meningitis, hiv ... DDX Tb meningitis ... sign on mri) HIV-infected ... T2 #MRI #Brain #clinical ... #radiology