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management hematology oncology syndromes lupus lymphocytic neurology sle antibodies classification comparison druginduced erythematosus gap globulin hemeonc hodgkins inflammatory lymphoma mds
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear Visual or auditory symptoms in conjunction
BEE Syndromes - ... less common diseases ... and treatment can ... Vogt-Koyanagi-Harada (VKH) disease ... disease • Multiple
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Positive ANA ≠ Autoimmune ... • +ANA can be seen ... context of other symptoms ... #patterns #rheumatology ... #diagnosis #differential
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... cells can indicate disease ... microglobulin Treatment ... #CLL #Chronic ... #diagnosis #workup
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... Leukemia (CLL) ... cytometry → >500/uL ... chemotherapy for low-risk disease ... lymphadenopathy and
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Systemic disease ... disease) Differential ... Arthritis, AS Treatment ... #Syndrome #diagnosis ... #rheumatology #
BEE Syndromes - Non-inflammatory Causes Immune-mediated conditions affecting the Brain, Eye, and Ear Visual or auditory symptoms in
BEE Syndromes - ... less common diseases ... underlying autoimmune ... and treatment can ... infections • Lyme disease
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Decade Skin Disease ... Diagnosis: • ANCA-associated ... tissue disease ... rheumatologic diseases ... ) • Kikuchi disease
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
any age) Autoimmune ... multisystemic disease ... associated with other diseases ... demyelinating disease ... Tracheobronchial disease
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
of autoantibodies ... months to years) Systemic ... • Evolution: Chronic ... disease Dr. ... #diagnosis #management
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis: • Systemic ... rheumatic diseases ... atherosclerotic disease ... most important diseases ... #Diagnosis #Rheumatology
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