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oncology disease lupus sle antinxp2 antinxp2dm autoimmune behcet chronic comparison dermatology dermatomyositis druginduced erythematosus hodgkins igg4 leukemia lymphocytic lymphoma monoclonal
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
female, asian • Systemic ... (antinuclear antibodies ... #diagnosis #management ... #phenotypes #workup ... #treatment #rheumatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... cells can indicate disease ... microglobulin Treatment ... #workup #oncology ... #hematology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
macular Vasculitis) Autoantibodies ... Evans • ITP • Cl-NH ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: ... • Anti-Ro/SSA autoantibodies ... permanent alopecia Differential ... Diagnosis: • ANCA-associated ... #Rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Systemic disease ... Asia • HLA-B51 association ... ) Differential Diagnosis ... #diagnosis #management ... #rheumatology #
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
of autoantibodies ... months to years) Systemic ... Evolution: Chronic disease ... comparison #table #rheumatology ... #diagnosis #management
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
ab • RF • Antinuclear ... Nephrogenic DI Hematologic ... Adenocarcinoma Treatment ... #Rheumatology # ... Diagnosis #Management
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma Workup ... number of sites of disease ... Hodgkin Lymphoma Treatment ... #hematology #oncology ... #management
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
without these autoantibodies ... had more severe disease ... • Myoglobin Association ... positive patients Treatment ... #management #rheumatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Gottron sign) ... (also seen in association ... Mechanic's hands Autoantibodies ... • Conduction system ... Myositis #Myopathy #rheumatology
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