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differential antibodies lupus management sle comparison erythematosus hematology igg4 monoclonal paraproteinemias phenotypes related rheumatic table testing treatment
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Disease! ... Rheumatic Diseases ... • Rheumatic Diseases ... #patterns #rheumatology ... #diagnosis #differential
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... Associated Rheumatic ... Diseases: • Homogeneous ... connective tissue disease ... #patterns #rheumatology
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
IgG4-Related Disease ... female, asian • Systemic ... , rheumatoid factor ... IgG4 #Related #Disease ... #phenotypes #workup
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
fever) and laboratory ... Decade Skin Disease ... Still disease, ... tissue disease ... diseases (i.e.
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... Diseases • Septic ... #Disease #Rheumatoid ... #Arthritis #laboratory ... #workup #diagnosis
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms, Arthritis ... of autoantibodies ... months to years) Systemic ... Evolution: Chronic disease ... #diagnosis #management
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Lymphoma (HCV) • CLL ... • Heavy Chain disease ... Evans • ITP • Cl-NH ... Sneddon-Wilkinson disease ... #Oncology
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