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ana antibodies autoimmune erythematosus hematology lupus management myopathy paraproteinemias sle
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
ANA ≠ Autoimmune Disease ... , Sjögren Syndrome ... , Myositis, Mixed ... #rheumatology # ... diagnosis #differential
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
Associated Rheumatic Diseases ... connective tissue disease ... Syndrome (SS), ... #rheumatology # ... diagnosis #differential
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... Evans • ITP • Cl-NH ... Sneddon-Wilkinson disease ... #Monoclonal #Differential ... #Diagnosis #Oncology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... multisystemic disease ... Syndrome Diagnosis ... demyelinating disease ... #Syndrome #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Decade Skin Disease ... diseases (i.e. ... (e.g. thyroid disease ... ) • Kikuchi disease ... • Castleman's disease
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Interstitial lung disease ... Interstitial lung disease ... Interstitial lung disease ... skeletal muscle disease ... myocarditis Other Diseases
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