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diagnosis hematology antibodies antinuclear bee complement cryoglobulins hypocomplementemia low mnemonic monoclonal myopathy myositis neurology oncology paraproteinemias size sle syndromes types
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Positive ANA ≠ Autoimmune ... : The ANA patterns ... lupus erythematosus ... lupus erythematosus ... #patterns #rheumatology
Classification of Vasculitis Vasculitis of large vessels - Arteritis temporalis (giant-cell arteritis) - Takayasu
Classification of ... arteritis - Inflammatory ... small vessels - ANCA-associated ... lupus erythematosus ... #Diagnosis #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
(Granulomatous disease ... rheumatic diseases ... lupus erythematosus ... atherosclerotic disease ... LFT • ESR • ANA
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear Visual or auditory symptoms in conjunction
less common diseases ... Vogt-Koyanagi-Harada (VKH) disease ... • Systemic lupus ... polychondritis • Behcet disease ... spectrum disorder • ANCA-associated
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Mnemonic C - Cryoglobulinemia ... Chain deposition disease ... Atypical HUS, autoimmune ... antiphospholipid syndrome ... Lupus Erythematosus
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... tissue disease ... rheumatologic diseases ... Serositis Labs: • ANA ... antibodies • (-) ANA
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
diseases: - 10% ... DDX: • ANCA (Antineutrophil ... lupus erythematosus ... diagnosis #types #classification ... #rheumatology #
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... diseases, such ... atherosclerotic disease ... most important diseases ... (GRANULOMATOUS DISEASE
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... ) Autoantibodies ... to cold IgG • Lupus ... Sneddon-Wilkinson disease ... #Monoclonal #Differential
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
• Anti-NXP2 (ANA ... Interstitial lung disease ... Interstitial lung disease ... Interstitial lung disease ... skeletal muscle disease
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