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diagnosis differential ana disease patterns erythematosus hematology laboratory lupus management monoclonal paraproteinemias phenotypes related rheumatic sle testing treatment
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... SLE), Sjogren's Syndrome ... • Rheumatic Diseases ... Syndrome, Myositis ... #patterns #rheumatology
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
and Associated Rheumatic ... Juvenile Idiopathic Arthritis ... SLE), Sjogren's Syndrome ... #Antibodies #ANA ... #patterns #rheumatology
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
IgG4-Related Disease ... female, asian • Systemic ... (antinuclear antibodies ... , rheumatoid factor ... #treatment #rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... affected joint • Systemic ... double-stranded DNA antibodies ... immunoglobulin G (IgG ... #Disease #Rheumatoid
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
• Anti-Ro/SSA autoantibodies ... ANCA-associated vasculitis, rheumatoid ... Non-autoimmune rheumatologic ... La, anti-Jo-1, SCL ... -70, RNP antibodies
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... macular Vasculitis) Autoantibodies ... Evans • ITP • Cl-NH ... anemia due to cold IgG ... Differential #Diagnosis #Oncology
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