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diagnosis differential disease lupus patterns comparison druginduced erythematosus laboratory phenotypes related rheumatic sjogrens table testing treatment
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
Associated Rheumatic ... Juvenile Idiopathic Arthritis ... ), Sjogren's Syndrome ... #Antibodies #ANA ... #patterns #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... Rheumatic Diseases ... • Rheumatic Diseases ... : Lupus (SLE), Systemic ... #Antibodies #ANA
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
IgG4-Related Disease ... female, asian • Systemic ... (antinuclear antibodies ... , rheumatoid factor ... #phenotypes #workup
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... affected joint • Systemic ... ) - Antinuclear ... antibodies, which ... #Disease #Rheumatoid
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... • Anti-Ro/SSA autoantibodies ... vasculitis, rheumatoid ... Non-autoimmune rheumatologic ... -70, RNP antibodies
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms, Arthritis ... 95% (IgG anti-chromatin ... of autoantibodies ... months to years) Systemic ... : Chronic disease
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... ab • RF • Antinuclear ... Arthritis Malignancy ... #Rheumatology # ... Diagnosis #Management
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