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disease management hematology lupus sle behcet cll comparison differential druginduced erythematosus igg4 leukemia lymphocytic monoclonal phenotypes related rheumatic rheumatoid signs
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... ) Autoantibodies ... Evans • ITP • Cl-NH ... #Differential #Diagnosis ... #Oncology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Systemic disease ... pathognomonic laboratory ... (Clinical Dx). ... Recurrent and chronic ... signs #symptoms #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... and fever) and laboratory ... • Anti-Ro/SSA autoantibodies ... with Lupus: • Chronic ... #Rheumatology
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
Clinical history ... female, asian • Systemic ... No necrosis, No vasculitis ... #phenotypes #workup ... #treatment #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms, Arthritis ... months to years) Systemic ... • Evolution: Chronic ... disease Dr. ... #diagnosis #management
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... affected joint • Systemic ... Screening Tests for Chronic ... ANA and RF (if clinical ... #laboratory #workup
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Orange or Hep C Clinical ... cells can indicate disease ... #workup #oncology ... #hematology
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