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diagnosis hematology causes hemolytic oncology algorithm workup agglutinin atlas bloodcell chronic classification cold common cvid extravascular gap globulin hemeonc hemolysis
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Nail Disorders secondary ... Iron deficiency anemia ... Diabetes Mellitus Half-and-Half ... Systemic #Secondary #dermatology ... #Differential #
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Iron deficiency anemia ... anemia (sometimes ... Unstable hemoglobin disorders ... RBC #Morphology #differential ... #diagnosis #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
) (e.g. lupus, CLL ... lymphoproliferative disorders ... Extravascular #Causes #differential ... #diagnosis #hematology ... #anemia
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
• Symptoms of anemia ... • hemolytic anemia ... malignancies -> CLL ... younger pts) Differential ... #hematology #diagnosis
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... Consider sickle cell ... Consider RBC membrane disorder ... #Differential #
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential ... PT, aPTT(liver disease ... changes), high MCV anemia ... not required in all ... #Differential #
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
leukemia in adults • Disorder ... 5) Symptoms of anemia ... chemotherapy for low-risk disease ... marrow failure with anemia ... hemeonc #diagnosis #management
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Immunodeficiency disorder ... to impaired B-cell ... autoimmune hemolytic anemia ... and M panel Management ... #diagnosis #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... Myeloproliferative Disease ... Neutropenia • Platelet Disorders ... blood count with differential ... Syndromes #diagnosis #hematology
Ileal Pouch Disorders - Differential Diagnosis • Surgical/Mechanical: Anastomotic leak, Pelvic sepsis, Sinus, Fistula, Strictures, Efferent
Ileal Pouch Disorders ... - Differential ... Lymphoma, Squamous cell ... Systemic/Metabolic: Anemia ... Diagnosis #surgery #gastroenterology
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