30 results
Hand, Foot, and Mouth Disease: A febrile illness (caused by Coxsackie Virus) associated vesicle formation on
Mouth Disease: A ... Goldberg, M.D. - UCSD ... Catalog of Clinical ... Images #Clinical ... #Dermatology #Pediatrics
Hemophagocytic Lymphohistiocytosis (HLH)
Clinical Features: Fever, Splenomegaly, Hepatomegaly, Lymphadenopathy, Confusion
Classic lab findings in HLH: ↑↑ ferritin, Anemia,
(HLH) Clinical ... Features: Fever, ... 8 criteria: • Fever ... triglycerides and ... Lymphohistiocytosis #diagnosis #hematology
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
RED FLAGS - In all ... suspicion of severe disease ... - Sickle cell disease ... #Limping #NWB #Algorithm ... #Child #Peds #Pediatrics
Clinical Algorithm for Emergency Department Evaluation and Management of UTI in Febrile Infants and Young Children

Urinary
Clinical Algorithm ... department with fever ... applicable for all ... not replace clinical ... #Fever
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Hemophagocytic Lymphohistiocytosis ... accumulation of clinical ... Assessment • Clinical ... : fever +++, hepatosplenomegaly ... • Autoimmune diseases
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... age, however the disease ... following: • Fever ... Low or absent NK cell ... management #treatment #hematology
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
clinical associations ... symptoms - Headache, fever ... doi: 10.1111/all ... Urticaria #diagnosis #rheumatology ... #comparison #table
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... Lymphadenopathy • Fevers ... cells can indicate disease ... and other C Cell ... workup #oncology #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
A subset of hemophagocytic ... • Periodic fever ... syndromes Clinical ... is the main clinical ... Diagnosis #Management #Hematology
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
 • Common Clinical Features: alveolitis, ear and
Somatic) Syndrome Clinical ... Syndrome: • Common Clinical ... thromboembolic disease ... , recurrent fevers ... (12%) • giant cell