16 results
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
No evidence of anemia ... immunoglobulin heavy-chain ... to the plasma cell ... #Significance #hematology ... #diagnosis #oncology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... hematemesis, melena, heavy ... changes), high MCV anemia ... #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Diagnosis: • ... lymphoproliferative disorders ... • Neutropenia, anemia ... #workup #oncology ... #hematology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Lymphoma (HCV) • CLL ... & MBL • Heavy ... (-) hemolytic anemia ... Paraproteinemias #Hematology ... #Oncology
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
40 ml/min A - Anemia ... diseases, CML, ... #Gammopathies #MGUS ... #diagnosis #hematology ... #oncology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
• Symptoms of anemia ... anemia • Cold ... significance (MGUS ... ), CLL, Myeloma ... #hematology #diagnosis
Anemia Diagnostic Algorithm

Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... Mean corpuscular (cell ... (BM) ablative disorders ... #Algorithm #Diagnosis ... #Workup #Hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
leukemia in adults • Disorder ... 5) Symptoms of anemia ... →several RCTs have ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Consider sickle cell ... Consider RBC membrane disorder ... #Algorithm #workup ... #hematology #testing
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... formed or don’t work ... Workup: • Complete ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology