11 results
diagnosis differential algorithm management aggregometry anemia causes chronic classification common cvid gammopathy gap globulin hemepath hemolytic hodgkins hypogammaglobulinemia immunodeficiency immunology
Inherited Qualitative Platelet Defects Bernard-Soulier Syndrome • Defect of adhesion due to a lack of GP Ib/IX/V
MYH9-Related Disorder ... structure and cell ... non-muscle myosin heavy ... #Defects #comparison ... differential #diagnosis #hematology
Platelet disorders and Aggregometry Glanzmann Thrombasthenia • Defective aggregation to all agonists except ristocetin • Normal platelet,
Platelet disorders ... aggregation to all ... afibrinogenemia, which will have ... with qualitative defects ... #disorders #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... hematemesis, melena, heavy ... not required in all ... Diagnosis #Causes #Workup ... #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Leukemia - Summary Cancer ... • M > F • Affects ... lymphoproliferative disorders ... Leukemia #diagnosis #workup ... #oncology #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Consider sickle cell ... with or without platelet ... Consider RBC membrane disorder ... Diagnosis #Algorithm #workup ... #hematology #testing
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... formed or don’t work ... Workup: • Complete ... Syndromes #diagnosis #hematology ... #oncology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
cancer for which ... immunoglobulin heavy-chain ... to the plasma cell ... #Significance #hematology ... #diagnosis #oncology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Immunodeficiency disorder ... to impaired B-cell ... • Affects 1:25,000 ... Lymphoma or other cancers ... hypogammaglobulinemia #immunology #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... Hodgkin Lymphoma Workup ... - Low Hb and platelets ... classification #hematology ... #oncology #management
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... Connective tissue disorders ... ovarian tumors, lung cancers ... gastric tumors • Hematology ... differential #diagnosis #hematology
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