14 results
Diabetes Pathophysiology and Medication Targets

The ominous octet is one concept that summarizes the different pathophysiologic pathways
Diabetes Pathophysiology ... commonly used diabetes ... ominous octet it works ... /ambcarerx #Diabetes ... Targets #Drug #Endocrinology
GLP-1 Agonists

Adlyxin (Lixisenatide) Daily
Bydureon (Exenatide ER) Weekly 
Ozempic (Semaglutide) Weekly 
Trulicity (Dulaglutide) Weekly 
Victoza (Liraglutide) Daily
to treat Type 2 Diabetes ... They work primarily ... upset (since it works ... Pharmacology #Dosing #Diabetes ... #DM2 #Endocrinology
SGLT2 Inhibitors 
SGLT2 inhibitors are the newest class of anti-diabetic medications, with the first one (Canagliflozin)
class of anti-diabetic ... These work by inhibiting ... Medications #DM2 #Diabetes ... #Endocrinology
Intraoperative Circulatory Embolus - Guidelines for Crises in Anaesthesia
Causes: thrombus, fat, amniotic fluid, air/gas.
Signs: hypotension, tachycardia,
EMBOLISM • “Mill wheel ... Embolism #VTE #Anesthesiology ... Diagnosis #Management #Workup
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
DPP4 inhibitors work ... Pharmacology #Management #Diabetes ... #DM2 #Endocrinology
Intraoperative Hypertension - Guidelines for Crises in Anaesthesia
Hypertension is most commonly due to inappropriate depth of
Feel the airway ... #Hypertension #Anesthesiology ... Diagnosis #Management #Workup
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
& shoe size, ↑ heel-pad ... Diagnosis and Workup ... Diagnosis #Management #Endocrinology
Intraoperative  Bradycardia - Guidelines for Crises in Anaesthesia
Bradycardia in theatre should not be treated as
Feel the airway ... #Bradycardia #Anesthesiology ... Diagnosis #Management #Workup
Intraoperative Tachycardia - Guidelines for Crises in Anaesthesia
Tachycardia in theatre is often due to inadequate depth
Feel the airway ... #Tachycardia #Anesthesiology ... Diagnosis #Management #Workup
Hypotension - Guidelines for Crises in Anaesthesia

Hypotension is commonly due to unnecessarily deep anaesthesia, the autonomic
Feel the airway ... #Differential #Anesthesiology ... Diagnosis #Management #Workup