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Thrombotic Microangiopathies In Systemic Lupus Erythematosus

Dr. Laurent ARNAUD @Lupusreference

#TMAs #Thrombotic #Microangiopathies #Systemic #Lupus #Erythematosus #SLE #hematology
Erythematosus #SLE #hematology ... #rheumatology # ... differential #diagnosis ... #causes
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Causes of Thrombocytosis ... - Differential ... disorders • Celiac disease ... Thrombocytosis #Differential ... #Hematology
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm
Sequestration:
 • Splenomegaly
Marrow Infiltration:
 • Hematologic and non-hematologic
Causes of Neutropenia ... Pancytopenia - Differential ... #Neutropenia #Differential ... Diagnosis #Algorithm #Causes ... #Hematology
Causes of Arterial and Venous Thrombosis - Differential Diagnosis Framework

STRUCTURAL:
 - PFO: paradoxical emboli
 - Popliteal
Causes of Arterial ... Venous Thrombosis - Differential ... artery aneurysm: Causes ... APLS:PLT ↓ HEMATOLOGIC ... Diagnosis #clots #hematology
Guidelines for Perioperative Management of Antirheumatic Medication in Patients with Rheumatic Diseases Undergoing Elective Total Hip
Perioperative Management ... with Rheumatic Diseases ... MithuRheum #rheumatology ... #autoimmune #pharmacology ... #table
Differential Algorithm for the Causes of thrombocytopenia 

#Diagnosis #Hematology #Thrombocytopenia #Causes #Differential
Differential Algorithm ... for the Causes ... #Diagnosis #Hematology ... Thrombocytopenia #Causes ... #Differential
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table

Warm AIHA (48-70%)
Cold AHA (16-32%)
 • Donath-Landsteiner HA (paroxysmal
Anemia (AIHA) - Differential ... Diagnosis Table ... Cold Agglutinin Disease ... #Diagnosis #Table ... #hematology
Diagnostic Schema for Hyperferritinemia

Pearl: Diseases associated with extreme elevations: 
1. HLH 
2. Still's disease 
3. Systemic
Hyperferritinemia Pearl: Diseases ... Still's disease ... Hyperferritinemia #Algorithm #Differential ... #Diagnosis #Hematology
Thrombocytosis - Differential Diagnosis
Platelet Count > 450
Reactive:
 • Anemia/blood loss (Fe deficiency)
 • Infection/Sepsis
 • Non-infectious
Thrombocytosis - Differential ... Non-infectious (malignancy, rheumatologic ... Thrombocytosis #Differential ... #Diagnosis #causes ... #Platelets #hematology
Causes of Neutropenia - Differential Diagnosis Algorithm
 • Decreased Neutrophils Only
 • Bicytopenia / Pancytopenia

#Neutropenia #Differential
Causes of Neutropenia ... - Differential ... #Neutropenia #Differential ... Diagnosis #Algorithm #Causes ... #Hematology