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rheumatology management syndromes algorithm bee chronic classification cll cord disorders erythematosus inflammatory leukemia lymphocytic mds monoclonal myelodysplasia paraproteinemias rhombencephalitis signs
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear Visual or auditory symptoms in conjunction
Inflammatory causes ... • Systemic lupus ... polychondritis • Behcet ... #neurology #inflammatory ... #differential #
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Anemia Clinical ... #Anemia #oncology ... #hematology #diagnosis
Rhombencephalitis BACTERIAL - Listeria (biphasic illness with bulbar dysfunction occurring later) - Mycobacterium tuberculosis - Pneumococcus - Brucella - Borrelia (Lyme Disease) -
- Behcet Disease ... - Systemic Lupus ... (bulbar symptoms ... #Diagnosis #Causes ... #Neurology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... • Anemia • Aplastic ... Myeloproliferative Disease ... #Syndromes #diagnosis ... #hematology #oncology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... : • Behçet Syndrome ... Diagnosis: Systemic ... Symptoms (Sx) in ... differential #diagnosis
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Systemic disease ... skin injury) • Neurologic ... syndrome (Clinical ... disease) Differential ... #Syndrome #diagnosis
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
et diutinum Neurologic ... (-) hemolytic anemia ... to cold IgG • Lupus ... Paraproteinemias #Hematology ... #Diagnosis #Oncology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... permanent alopecia Differential ... : • Symptoms limited ... Chronic B-cell activation ... #Diagnosis #Rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... Differential Diagnosis ... tract, and often causes ... • Behcet syndrome ... #Differential #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... with no early symptoms ... • Neutropenia, anemia ... #workup #oncology ... #hematology
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