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liver obstetrics pregnancy algorithm biliary chemistry cholangitis cirrhosis comparison disease hellp injury interpretation lfts management obgyn primary rvalue transaminitis workup
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
(DIC, ascites, jaundice ... Antithrombin Ill • Ultrasound ... infiltration) Differential ... Hepatitis, Preeclampsia ... Pregnancy #hepatology
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Pruritus, Mild jaundice ... Hepatic infarcts, Hematomas ... #obstetrics #hepatitis ... #comparison #differential ... #diagnosis #icp
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Liver Injury - Differential ... Diagnosis Algorithm ... , PBC, PSC, IgG4 ... hemolysis, bleeding, hematoma ... #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Pathophysiology ... hyperpigmentation • Jaundice ... bile ducts Differential ... Viral hepatitis, ... #workup #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Check Acute viral hepatitis ... hemolysis, bleeding, hematoma ... liver #chemistry #diagnosis ... #differential # ... Hepatology #transaminitis
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