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obstetrics biliary causes cholangitis cirrhosis comparison disease fatty injury liverenzymes management obgyn workup
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Pruritus, Mild jaundice ... Hepatic infarcts, Hematomas ... of Pregnancy (AFLP ... diagnosis #icp # ... HELLP #AFLP
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... Diagnosis Algorithm ... • Wilson's • Pregnancy ... - AFLP, HELLP ... Diagnosis #Algorithm
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Diagnosis Algorithm ... : HELLP • Iatrogenic ... hemolysis, bleeding, hematoma ... diagnosis #algorithm ... #hepatology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... (DIC, ascites, jaundice ... Hepatitis, Preeclampsia ... , HELLP, Intrahepatic ... Pregnancy #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Pathophysiology ... hyperpigmentation • Jaundice ... Viral hepatitis, ... cholestasis of pregnancy ... #workup #hepatology
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