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obstetrics algorithm chemistry cholangitis cirrhosis disease fatty hellp icp injury interpretation lfts management obgyn pbc primary transaminitis workup
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Hepatic infarcts, Hematomas ... of Pregnancy (AFLP ... #hepatitis #comparison ... #differential # ... diagnosis #icp #
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... Antithrombin Ill • Ultrasound ... infiltration) Differential ... Hepatitis, Preeclampsia ... Pregnancy #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... Diagnosis Algorithm ... melanoma, myeloma • Pregnancy ... hemolysis, bleeding, hematoma ... #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
hemolysis, bleeding, hematoma ... #chemistry #diagnosis ... #differential # ... Hepatology #transaminitis ... #LFTs #RValue #
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... bile ducts Differential ... Viral hepatitis, ... cholestasis of pregnancy ... #workup #hepatology
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