479 results
The Mechanism of Small Interfering RNA (siRNA) Therapy. Synthetic double-stranded RNA containing an ALAS1-specific sequence is
exclusively on hepatocytes ... Within the hepatocyte ... #Pathophys #Honc
Main types of organ-specific injuries after an electric shock #Diagnosis #Pathophys #EM #Burn #IM #ElectricShock #ElectricalInjury
shock #Diagnosis #Pathophys ... #EM #Burn #IM #
Catecholamine Vasopressor Effect Sites and Indications #Pathophys #Management #EM #IM #PCC #Catecholamine #Comparison #Table #Epi #Norepi
and Indications #Pathophys ... #Management #EM
Methanol and Metabolism #Pathophys #EM #Tox #Alcohol #Metabolism #Methanol #EthyleneGlycol #Formate #Oxalate #AldehydeDehydrogenase #Fomepizole
and Metabolism #Pathophys ... #EM #Tox #Alcohol
Mechanisms of Lower Extremity Edema: #Diagnosis #Pathophys #EM #IM #Edema #Lower #LowerExtremity #Causes #Starling #Oncotic #Hydrostatic
Edema: #Diagnosis #Pathophys ... #EM #IM #Edema
Metabolism of alcohols #Pathophys #EM #Tox #Alcohol #Metabolism #Methanol #EthyleneGlycol #Isopropyl #Formate #Oxalate #AldehydeDehydrogenase #ALiEM
Metabolism of alcohols #Pathophys ... #EM #Tox #Alcohol
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
Synthesis: in hepatocyte ... accumulation in hepatocyte ... from albumin upon hepatocyte ... conjugation in hepatocyte ... reuptake into hepatocyte
Pathology - Hepatocyte Pigments

Lipofuschin (H&E) 

Alpha-I-antitrypsin globules (PAS-D) 

Mallory's hyaline / Mallory Denk Bodies 

Giant Mitochondria
Pathology - Hepatocyte ... bilirubinostasis (H&E) #Hepatocyte
N-Acetyl Cysteine (NAC) Therapy Mechanism of Action: The non-toxic route of APAP metabolism gets saturated in
the extent of hepatocyte ... #Pathophys #Toxicology
Pathyophysiology - hyperglycemic crises in patients with diabetes 
Key signs/symptoms of HHS/DKA:
Both: Polyuria, polydipsia, weight loss,
coma, seizure) #Pathophys ... #EM #IM #Endo #