17 results
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
imaging: Hepatic ... extensive necrosis and hemorrhage ... often <5 mg/dL, higher ... obstetrics #hepatitis #comparison ... #differential #
Appearance of Liver Lesions on Various Imaging Modalities
 • Computed Tomography (CT) - Arterial Phase, Portal
Appearance of Liver ... , Metastasis #Liver ... #Lesions #Hepatic ... POCUS #radiology #differential ... #diagnosis #comparison
Portal venous gas on hepatic ultrasound: A concerning finding in the critically ill patient that should
venous gas on hepatic ... ultrasound: A concerning ... reflection on the differential ... of air in the hepatic ... #hepatology #liver
Appearance of Liver Lesions on Computed Tomography (CT) - Arterial Phase, Portal Venous Phase and Delayed
Appearance of Liver ... , Metastasis #Liver ... #Lesions #Hepatic ... CT #radiology #differential ... #diagnosis #comparison
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
ALP) Elevation - Differential ... disturbance (obstructed liver ... phosphatase sources: - Highest ... • Bone • Liver ... elevation DDX of Hepatic
Appearance of Liver Lesions on Contrast Enhanced Ultrasound - Early arterial, Grayscale phase, Late arterial phase,
Appearance of Liver ... Contrast Enhanced Ultrasound ... #Lesions #Hepatic ... POCUS #radiology #differential ... #diagnosis #comparison
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Differential Diagnosis ... Pre-analytical cause (e.g. heparin ... thrombin inhibitors, heparin ... • Reduced liver ... • Massive hemorrhage
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Early liver disease ... unfractionated heparin ... Reduced liver synthesis ... Massive hemorrhage ... Causes #diagnosis #differential
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
cholestasis → Cirrhosis/Liver ... titer 1:40 or higher ... • Liver biopsy ... bile ducts Differential ... malignancies, Hepatic
Postpartum Hemorrhage - Differential Diagnosis and Management 
Uterine Atony (80%) - Most PPH Will respond to
Postpartum Hemorrhage ... - Differential ... Oxytocin 40 IU in 1 liter ... compression (using ultrasound ... #Differential #