18 results
Trials Comparing Short- vs Longer-Course Antibiotics 
... Have Shown Short-Course is JUST AS EFFECTIVEI 
Source Editorial:
Comparing Short- vs Longer-Course ... Antibiotics .. ... #Course #Antibiotics ... #Duration #EBM ... #Stewardship #InfectiousDiseases
Antibiotic Stewardship: Shorter is Better 
CAP 
HAP 
VAP 
Intra-abd 
Gram Neg Bacteremia 
AECB 
Cellulitis 
Osteo 
Septic
Antibiotic Stewardship ... BradSpellberg #Shorter #Longer ... #Course #Antibiotics ... #Duration #EBM ... #Stewardship #InfectiousDiseases
Daptomycin  - Antibiotics Class Overview

Mechanism: Lipopeptide antibiotic – forms transmembrane channels and depolarizes cells.
Daptomycin - Antibiotics ... Class Overview ... Spectrum: only covers ... cidal nature) #Pharmacology ... #Overview #Daptomycin
Antibiotic Stewardship: Shorter is Better
CAP 3-5d = 5-14d
VAP 8d = 15d
Intra-abd 5 or 7d = 10
Antibiotic Stewardship ... BradSpellberg #Shorter #Longer ... #Course #Antibiotics ... #Duration #EBM ... #Stewardship #InfectiousDiseases
ANTIBIOTIC SUSCEPTIBILITIES IN INTENSIVE CARE

Antibiotic spectra made simple(r). Version 2, now updated with new bugs &
ANTIBIOTIC SUSCEPTIBILITIES ... INTENSIVE CARE Antibiotic ... Care Unit) PDF Source ... CriticalCare #Overview ... #Pharmacology #
Linezolid (Zyvox) (PO and IV) - Antibiotics Class Overview

Mechanism: Oxazolidinone class –unique ribosomal inhibitor (acts on
(PO and IV) - Antibiotics ... Class Overview ... Spectrum: covers ... infections #Pharmacology ... #Antibiotics #Review
Synercid (Quinupristin/Dalfopristin) (IV) - Antibiotics Class Overview

Mechanism: “Streptogramins”– inhibits sequential steps in ribosomal synthesis
Spectrum: covers MRSA
Dalfopristin) (IV) - Antibiotics ... Class Overview ... synthesis Spectrum: covers ... #Pharmacology #Antibiotics ... #Review #Overview
Antifungal Echinocandins  - Antibiotics Class Overview

Mechanism: Inhibit glucan synthesis in fungal cell wall by blocking
Echinocandins - Antibiotics ... Class Overview ... Candida infections – covers ... Anidulafungin #Pharmacology ... #Antibiotics #Review
Practice Guidelines for Preoperative Fasting

Infographic by Dr. Jesse Burk-Rafel
@jbrafel

> 8 hours - Heavy foods (fried/fatty) and
@jbrafel > 8 hours ... patient thirst and hunger ... - LOWER risk ... and the Use Of pharmacologic ... #Timeline #EBM
The following table from MacGregor (1997) summarizes the bioavailability of many commonly used antibiotics:
#EBM #Pharmacology #InfectiousDiseases
commonly used antibiotics ... : #EBM #Pharmacology ... #InfectiousDiseases ... #Oral #Antibiotics