7 results
Antifungal Echinocandins  - Antibiotics Class Overview

Mechanism: Inhibit glucan synthesis in fungal cell wall by blocking
glucan synthesis in fungal ... Candida infections – covers ... Static vs Aspergillus ... > 2nd-line for Aspergillus ... Echinocandins lack activity
Allergic Bronchopulmonary Aspergillosis (ABPA)
WHAT IS IT?
Hypersensitivity response to Aspergillus fumigatus in the airways
 • Primarily affects
cystic fibrosis • Aspergillus ... • Presence of Aspergillus ... corticosteroids +/- anti-fungal ... Aspergillosis #ABPA #pulmonary ... #diagnosis #management
Invasive Aspergillus (IA) - Diagnosis and Management
Aspergillus is ubiquitous in nature. Most invasive infections are caused
Invasive Aspergillus ... Diagnosis and Management ... presentations: • Pulmonary ... IA #Diagnosis #Management ... #treatment #fungal
For my UME micro course, I made a figure that captures this terminology and lets learners
contrast spectra of activity ... In this final figure ... – green means active ... dark blue means active ... #pharmacology #management
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Recent infection • Pulmonary ... infection (NTM) • Fungal ... • HIV: 2/3 pulmonary ... destruction (including pulmonary ... TB #Diagnosis #Management
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Recent infection • Pulmonary ... infection (NTM) • Fungal ... • HIV: 2/3 pulmonary ... destruction (including pulmonary ... TB #Diagnosis #Management
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
Diagnosis: • Direct fungal ... ASPERGILLOSIS • Aspergillus ... arthroconidia; the fungus ... InfectiousDiseases #Fungal ... #Diagnosis #Management