5 results
Fungal biomarkers
Beta-d-glucan
Aspergillus galactomannan

By Dr. Sara Dong @swinndong via Febrile [febrilepodcast.com]

#ID  #Infectious Diseases  #Infections
#Differential #Ddx
febrilepodcast.com] #ID ... #Infections #Differential ... #Ddx #Diagnosis ... #Fungal #Fungi ... #BDG #BDGlucan #
ID Ddx: Diarrhea in a transplant recipient
- Bacterial: C.diff, Campy, Salmonella, Aeromonas, E.coli
- Viral: CMV, noro,
ID Ddx: Diarrhea ... #Infections #Differential ... #Ddx #Diagnosis ... Diarrhea #Transplant #TxID ... #SOT #Causes
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan
Beta-D-Glucan:
 • Polysaccharide cell wall component of many fungi
 • Pathogens:
component of many fungi ... invasive fungal infection ... increase BDG!) ... differentiate colonization ... setting of GVHD) ID
Timeline of infections after solid organ transplantation can roughly be broken up into three time periods:
febrilepodcast.com] #ID ... #Infections #Differential ... #Ddx #Diagnosis ... #Transplant #TxID ... #SOT #Comparison
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives
1,3-Beta-D-Glucan
 • Cell wall component of many fungi
component of many fungi ... surfaces, Albumin, Infections ... Spec 81% for dx ... differentiate colonization ... closely related fungi