5 results
Fungal biomarkers
Beta-d-glucan
Aspergillus galactomannan

By Dr. Sara Dong @swinndong via Febrile [febrilepodcast.com]

#ID  #Infectious Diseases  #Infections
#Differential #Ddx
febrilepodcast.com] #ID ... #Infections #Differential ... #Ddx #Diagnosis ... Fungal #Fungi #BDG ... #Candida #Microbiology
ID Ddx: Diarrhea in a transplant recipient
- Bacterial: C.diff, Campy, Salmonella, Aeromonas, E.coli
- Viral: CMV, noro,
ID Ddx: Diarrhea ... #Infections #Differential ... #Ddx #Diagnosis ... Diarrhea #Transplant #TxID ... #SOT #Causes
Timeline of infections after solid organ transplantation can roughly be broken up into three time periods:
#Infections #Differential ... #Ddx #Diagnosis ... #Transplant #TxID ... #SOT #Comparison ... #Microbiology
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan
Beta-D-Glucan:
 • Polysaccharide cell wall component of many fungi
 • Pathogens:
Specificity: - Serum BDG ... invasive fungal infection ... increase BDG!) ... differentiate colonization ... setting of GVHD) ID
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives
1,3-Beta-D-Glucan
 • Cell wall component of many fungi
use: Candida, Aspergillus ... TBDG), Use of cellulose ... surfaces, Albumin, Infections ... Spec 81% for dx ... differentiate colonization