7 results
Fungal biomarkers
Beta-d-glucan
Aspergillus galactomannan

By Dr. Sara Dong @swinndong via Febrile [febrilepodcast.com]

#ID  #Infectious Diseases  #Infections
#Differential #Ddx
Beta-d-glucan Aspergillus ... febrilepodcast.com] #ID ... #Infections #Differential ... #Ddx #Diagnosis ... #Fungal #Fungi
ID Ddx: Diarrhea in a transplant recipient
- Bacterial: C.diff, Campy, Salmonella, Aeromonas, E.coli
- Viral: CMV, noro,
ID Ddx: Diarrhea ... #Infections #Differential ... #Ddx #Diagnosis ... Diarrhea #Transplant #TxID ... #SOT #Causes
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan
Beta-D-Glucan:
 • Polysaccharide cell wall component of many fungi
 • Pathogens:
component of many fungi ... infection (IFI) ... differentiate colonization ... closely related fungi ... setting of GVHD) ID
Timeline of infections after solid organ transplantation can roughly be broken up into three time periods:
febrilepodcast.com] #ID ... #Infections #Differential ... #Ddx #Diagnosis ... #Transplant #TxID ... #SOT #Comparison
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives
1,3-Beta-D-Glucan
 • Cell wall component of many fungi
component of many fungi ... surfaces, Albumin, Infections ... Spec 81% for dx ... differentiate colonization ... closely related fungi
Soil Related Infections - Differential Diagnosis Framework

Mechanism Of Infection:
 • Wound
 • GI: Ingestion, MUD, Contaminated
- Differential ... include: bacteria, fungi ... • Chlorella Fungi ... Soil-related endemic fungi ... pulmonary disease • Aspergillus
Conditions Associated With Hyperferritinemia 
DDx of extreme hyperferritinemia >10,000
Not just HLH - in fact, most common
Hyperferritinemia DDx ... hyperferritinemia >10,000 Not ... - Infection-Fungai ... - Diagnosis Not ... Hyperferritinemia #differential