39 results
diagnosis differential algorithm endocrinology causes pathophysiology signs symptoms adrenal gynecomastia workup hematology hyperplasia management pharmacology syndrome urology androstenedione aromatase benign
Congenital Adrenal Hyperplasia - 21-Hydroxylase Deficiency - Signs and Symptoms • Brain: Androgenization effects, Glucocorticoid effects,
Hyperplasia - 21-Hydroxylase ... Reproductive: Gonadal hypofunction ... #Hyperplasia #Hydroxylase
ACTH LH Cholesterol cholesterol desmolase Pregnenolone 17a-hydroxylase 17 Hydroxyregnenolone 17,20-lyase 3B-hydroxysteroid dehydrogenase 3B-hydroxysteroid dehydrogenase 17a-hydroxylase #Progesterone 17-Hydroxyprogesterone 17,20-lyase 21ß-hydroxylase 21ß-hydroxylase 11-Deoxycorticosterone 11-Deoxycortisol 11ß-hydroxylase 11ß-hydroxylase #Cortisol #Dehydroepiandrosterone #DHEA 3ß-hydroxysteroid dehydrogenase 个 #Androstenedione #17B-hydroxysteroid #dehydrogenase #Testosterone #aromatase #FSH #Estradiol #5a reductase #Corticosterone aldosterone synthase #Aldosterone Angiotensin || #Dihydrotestosterone (DHT)
Pregnenolone 17a-hydroxylase ... 17,20-lyase 21ß-hydroxylase ... 21ß-hydroxylase ... 11ß-hydroxylase ... dehydrogenase #Testosterone
Exogenous Testosterone Side Effects • Mood disorder, Depression, Aggression • ↑ Erythropoiesis • Hypogonadism +/-BPH, prostate
Exogenous Testosterone ... #Exogenous #Testosterone
Secondary causes of Hypertension • Medications, Drugs, Chemo: NSAIDS, Steroids, CNI, Alcohol, Cocaine, OCP, Licorice, MAOI,
Syndrome, 11B hydroxylase ... def, 17alpha hydroxylase
Hypogonadism Differential Diagnosis Algorithm • Low testosterone, Normal or low LH, Normal or low FSH -
Algorithm • Low testosterone ... hypogonadism • Normal testosterone ... etiologies • Normal testosterone ... disease • Low testosterone ... Algorithm #Low #Testosterone
Cushing Syndrome Testing Algorithm INDICATIONS FOR TESTING: • Suspected Cushing syndrome (central obesity, muscle weakness, refractory hypertension) Testing:
endocrinology #Adrenal #Hyperfunction
Medications associated with neuroleptic malignant syndrome First-generation and second-generation antipsychotics are dopamine receptor antagonists, which produce a
of dopaminergic hypofunction
Benign Prostatic Hyperplasia: Pathogenesis and Medications Aging -> Increased Testosterone -> Testosterone metabolized into DHT by type
-> Increased Testosterone ... -> Testosterone ... Conversion of testosterone ... pituitary -> Decr Testosterone
Anemia - Underproduction Diagnostic Algorithm - Iron deficiency anemia - Anemia of chronic inflammation - Anemia
TSH, LFTs, +/- testosterone
#LH #Cholesterol t cholesterol desmolase (#thecal cells) V 3ß-hydroxysteroid dehydrogenase Pregnenolone Progesterone 17a-hydroxylase 17-Hydroxypregnenolone 17,20-lyase Dehydroepiandrosterone 3ß-hydroxysteroid dehydrogenase #Androstenedione 17B-hydroxysteroid dehydrogenase FSH V #Testosterone Đ #aromatase (granulosa cells) V #Estradiol
Progesterone 17a-hydroxylase ... dehydrogenase FSH V #Testosterone
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