8 results
Primary Biliary Cirrhosis - Pathophysiology
Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish
Epigentics Risk
Primary Biliary ... BEC injury - Loss ... BECs and gradual loss ... Cholestasis #PBC #Primary ... #hepatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Primary Biliary ... 65 years PBC Pathophysiology ... bile ducts • Loss ... #Biliary #Cirrhosis ... diagnosis #workup #hepatology
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
CPPD vs Gout ... disease states Pathophysiology ... deposit and can activate ... swelling, pain, loss ... Gout #Comparison #rheumatology
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... Lung abscess Primary ... Primary Tuberculosis ... Fever • Weight loss ... assay (IGRA) • PPD
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... Lung abscess Primary ... Primary Tuberculosis ... Fever • Weight loss ... assay (IGRA) • PPD
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
chronic pain • loss ... nephrocalcinosis • CPPD ... collection with EDTA Pathophysiology ... • Elevation of urinary ... Hyophosphatasia #hepatology
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
) Pathophysiology ... calcium to form CPP ... deposit and can activate ... swelling, pain, loss ... Deposition #Disease #Rheumatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Vaginal dryness • Primary ... eyes • Salivary hypofunction ... biliary cirrhosis ... Nephrogenic DI Hematologic ... muscarinic agonists • Active