11 results
Primary Biliary Cirrhosis - Pathophysiology
Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish
Epigentics Risk
relative with PBC ... BEC injury - Loss ... BECs and gradual loss ... Cholestasis #PBC ... #hepatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Primary Biliary ... Pathophysiology ... bile ducts • Loss ... bile ducts Differential ... diagnosis #workup #hepatology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
ALP) Elevation - Differential ... Diagnosis Algorithm ... Cholangitis (PBC ... - Other biliary ... #hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Function Tests - Differential ... Diagnosis Algorithm ... Ducts - PBC ... - CBD stone, Biliary ... #diagnosis #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Liver Injury - Differential ... Diagnosis Algorithm ... Autoimmune hepatitis, PBC ... stone, Malignancy, PBC ... #hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Liver Injury - Differential ... hepatitis, Acute biliary ... Malignancy, 1° PBC ... Causes #Acute #algorithm ... #hepatology
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Approach to Anemia - Differential ... Diagnosis Algorithm ... Blood Loss ... #Diagnosis #Algorithm ... #Causes #Hematology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Liver Enzymes - Differential ... Diagnosis Algorithm ... Bile Ducts • PSC ... Duct Stone • Biliary ... Others #LFTs #Hepatology
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased Heme Synthesis or
Volume (MCV) - Differential ... Diagnosis Algorithm ... Chronic Blood Loss ... #Diagnosis #Algorithm ... #Causes #Hematology
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
neutrophils are slightly less ... Neutrophil (Normal) Differential ... #Bandemia #differential ... #CBC #hematology ... #pathophysiology