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diagnosis hepatology differential management activetb cirrhosis dermatology latenttb pbc primary rheumatology tb treatment tuberculosis alkaline alopecia alp calcium causes cholangitis
Primary Biliary Cirrhosis - Pathophysiology Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish Epigentics Risk
female-predominant disease ... of autoimmune disease ... BEC injury - Loss ... BECs and gradual loss ... #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary ... 65 years PBC Pathophysiology ... bile ducts • Loss ... but elevated as disease ... diagnosis #workup #hepatology
Vesiculobullous Rashes - THE ALGORITHMIC APPROACH Vesiculobullous rashes provoke significant angst in many physicians (Figure 5, page
Vesiculobullous Rashes - THE ALGORITHMIC ... disseminated gonococcal disease ... hand-foot-and-mouth disease ... is simpler and less ... #Diagnosis #Dermatology
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm DIFFUSE Scarring - Irreversible-biopsy required • Lupus
Hair Loss (Alopecia ... Differential Diagnosis Algorithm ... Secondary to Skin Disease ... HairLoss #Alopecia #dermatology ... Differential #Diagnosis #Algorithm
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
CPPD vs Gout ... • Underlying disease ... states Pathophysiology ... swelling, pain, loss ... Gout #Comparison #rheumatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Differential Diagnosis Algorithm ... Extrahepatic - Biliary ... Injury: • AST: Less ... differential #diagnosis #algorithm ... #hepatology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
chronic pain • loss ... nephrocalcinosis • CPPD ... Malnutrition • Wilson's disease ... collection with EDTA Pathophysiology ... Hyophosphatasia #hepatology
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD) Pathophysiology: Pyrophosphate produced by chondrocytes likely precipitates with calcium to
Pyrophosphate Deposition Disease ... (CPPD) Pathophysiology ... • Underlying disease ... swelling, pain, loss ... #Rheumatology #
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... bacteremia, and miliary ... Fever • Weight loss ... Hematogenous spread -> Miliary ... assay (IGRA) • PPD
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... bacteremia, and miliary ... Fever • Weight loss ... Hematogenous spread -> Miliary ... assay (IGRA) • PPD
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