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diagnosis causes treatment blood comparison hematology pharmacology product reactions algorithm binding gitelman hypokalemia kdigo medications pathophysiology rhabdomyolysis syndrome transfusion transfusions
Potassium-Binding Agents to Treat Hyperkalemia Sodium zirconium cyclosilicate (Lokelma): • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... and sodium • Dosing ... patients sensitive to high ... of aspiration #Potassium ... #pharmacology #table
Potassium Binders for Management of Hyperkalemia • SPS - Sodium polystyrene sulfonate • Patiromer (veltassa) •
Potassium Binders ... for Management ... #Binders #Management ... #pharmacology #table ... #comparison #nephrology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... Clenching of fist during ... phlebotomy High ... #differential # ... #high #nephrology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... Clenching of fist during ... phlebotomy High ... #differential # ... #high #nephrology
KDIGO Treatment algorithm for management of acute hyperkalemia in the emergency department • Place on cardiac
algorithm for management ... of acute hyperkalemia ... • Consider K+ binder ... #treatment #potassium ... #high #nephrology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Rhabdomyolysis - Differential ... Framework and Management ... Monitor potassium ... per day until stable ... causes #treatment #nephrology
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
hypokalemic salt-losing ... (renal potassium ... ratio 0.5%) Differential ... Syndrome #diagnosis #nephrology ... #management #pathophysiology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
High mortality. ... Hypocalcemia, Hyperkalemia ... Citrate in RBCs binds ... products contain potassium ... Transfusion #diagnosis #management
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
High mortality. ... Hypocalcemia, Hyperkalemia ... Citrate in RBCs binds ... products contain potassium ... Transfusions #diagnosis #management
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