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differential causes potassium algorithm binders comparison high hypomagnesemia hyponatremia management classification drugs hypomg magnesium pathophysiology treatment binding constipation diuresis diuretics
Potassium-Binding Agents to Treat Hyperkalemia Sodium zirconium cyclosilicate (Lokelma): • Mechanism: Preferentially captures K in exchange for
Agents to Treat Hyperkalemia ... to moderate); hypokalemia ... Hypomagnesemia; hypokalemia ... Potassium #Binding #Hyperkalemia ... #medications #pharmacology
Hypokalemia - Differential Diagnosis Algorithm Transcellular Shift: • Alkalosis • ↑ beta-2 adrenergic simulation • Erythropoiesis
Hypokalemia - Differential ... Diagnosis Algorithm ... Thyrotoxicosis Medications ... MatthewHoMD #Hypokalemia ... #Algorithm #nephrology
Drugs causing hyperkalemia • Impaired release of renin: NSAIDs, Beta blockers, Cyclosporine, tacrolimus, Diabetes, Elderly •
Drugs causing hyperkalemia ... Ketoconazole • Sodium ... Drospirenone #Drugs #hyperkalemia ... #medications #causes ... #differential #diagnosis
Etiologies of Hypernatremia - Differential Diagnosis GI losses / Insensible losses Sodium Overload Transcellular Movement of Water Central Diabetes Insipidus
- Differential Diagnosis ... Insensible losses Sodium ... in kidneys) - Medications ... - Chronic hypokalemia ... #Table #Causes
Potassium Binders for Management of Hyperkalemia • SPS - Sodium polystyrene sulfonate • Patiromer (veltassa) •
Management of Hyperkalemia ... Binders #Management #Hyperkalemia ... #treatment #pharmacology ... #table #comparison ... #nephrology
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... (Heparin) • Sodium-channel ... MunerMohamed1 #hyperkalemia ... #differential #diagnosis ... #potassium #medications
Hypomagnesemia - Etiologies by Mechanism Decreased GI Uptake - Poor dietary intake (particularly common in alcoholics)
Renal Loses - Medications ... - Hypokalemia ... - Uncontrolled diabetes ... #Low #Magnesium ... #Table #Classification
Drugs associated with hypokalemia and hypomagnesemia Hypokalemia - Shift from extracellular fluid to intracellular fluid compartment -
associated with hypokalemia ... hypomagnesemia Hypokalemia ... overdose) - Sodium ... panitumumab) #Drugs #hypokalemia ... #nephrology #Causes
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... Suspicion for Hyperkalemia ... Drugs Causing Hyperkalemia ... Metabolic acidosis - Hyperkalemia ... cantaloupe #hyperkalemia
Hypomagnesemia - Differential Diagnosis Renal Causes of Hypomagnesemia - Familial: Bartter syndrome and Gitelman syndrome, Isolated recessive hypomagnesemia,
with secondary, hypocalcemia ... Hypomagnesemia - Acquired: Medications ... pentamidine), Hypercalcemia ... #causes #nephrology ... #magnesium #low
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