4 results
Classification of COVID-19 Disease States and Potential Therapeutic Targets

Viral Response Phase -> Host Inflammatory Response Phase
Stage
Classification of ... Infection) Stage II (Pulmonary ... Phase) Stage Ill ... #Progression #Classification ... #Diagnosis #Pathophysiology
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... staining): • Low Complement ... Idiopathic • Normal Complement ... With associated pulmonary ... differential #diagnosis #algorithm
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
antigen, leading to complement ... Type Ill - IgG and ... Complement activation ... Hypersensitivity #Types #Classification ... #Pathophysiology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
progressing GN • New pulmonary ... often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... against MPO • Complement ... #rheumatology #classification