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diagnosis allergy classification differential pathophysiology reactions rheumatology vasculitis hypersensitivityreaction immunology management table allergic boop causes comparison cop cryoglobulinemia cryoglobulins cryptogenic
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
of hypersensitivity ... Anaphylaxis, Hay fever ... Antigen-antibody complex ... Antigen-antibody complexes ... they activate complement
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
Hypersensitivity ... , seasonal hay fever ... antigen, leading to complement ... Antigen-antibody complexes ... Complement activation
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
: Summary Type ... peanuts), Hay fever ... conjunctivitis Type ... Graves' Disease Type ... Antigen-Ab immune complexes
Type II Hypersensitivity: Pathogenesis and clinical findings Definition: When antigens bind to the body's cell surfaces, forming
Type II Hypersensitivity ... antigen-surface complex ... activates the complement ... cell surfaces #Type2 ... #Type2 #HypersensitivityReaction
Algorithm for the differentiation between simple and complex febrile seizures. Guidelines for evaluation of each. #Diagnosis
Algorithm for the ... between simple and complex ... FebrileSeizure #Fever ... #Workup #Simple ... #Complex
Type I Hypersensitivity: Pathogenesis and clinical findings Definition: Production of lgE Antibodies that bind to harmless allergens
Type I Hypersensitivity ... allergen-antibody complex ... Allergen-antibody complexes ... peanuts) • Hay fever ... Anaphylaxis #TypeI
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
deposit of immune complexes ... Types: • Type ... • Type III Often ... • Low serum C4 complement ... vasculitis • Hypersensitivity
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tracts Immune Complex ... Urticaria and hypocomplementemia ... Coronary arteries - Fever ... Vasculitis: • Fevers ... against MPO • Complement
Cryptogenic Organizing Pneumonia (COP) Cryptogenic Organizing Pneumonia Overview: • Idiopathic form of organizing pneumonia • formerly BOOP
formerly BOOP • Type ... cough, dyspnea, fever ... other processes Workup ... strep, HIV • CTD workup ... interstitial pneumonia’s, Hypersensitivity
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis: • Fevers ... pauci-immune GN Immune Complex ... Elevated AST ALT • Hypocomplementemia ... Vasculitis) • Hypocomplementemic ... inflammation Hypersensitivity
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