14 results
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Mechanism of Action: Allergen-specific ... lgE causes mast-cell ... antigens, leading to complement ... they activate complement ... #types #allergy
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
reactionType ... reactionType ... reactionType ... An allergic reaction ... #Allergic #Reactions
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Soluble antigen - Allergen-specific ... When the specific allergen ... antigen, leading to complement ... Complement activation ... #Diagnosis #Reactions
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... glomerulonephritis, type ... 1 (50%-80%), type ... @AnnKumfer #Hypocomplementemia ... #Low #Complement
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
Type IV Hypersensitivity ... causes development ... of allergen-specific ... Allergic reaction ... ivy) #TypeIV #Type4
Angioedema - Classification Diagnosis and Treatment
Types of Angioedema:
 • Acute allergic angioedema - Usually occurs with
and Treatment Types ... exposure • Non-allergic ... drug reaction - ... cell-mediated in > 90% of cases ... Classification #Types
Penicillin Allergy Pathway for Antibiotic Prescription in Patients With Penicillin Allergy
Mild Reaction - Itching, Minor rash
Mild Reaction ... Use carbapenem Type ... urticaria OR Unknown reaction ... Type II-IV HSR ... #Prescription #algorithm
Type II Hypersensitivity: Pathogenesis and clinical findings
Definition: When antigens bind to the body's cell surfaces, forming
Type II Hypersensitivity ... antibody-mediated immune reaction ... activates the complement ... cell surfaces #Type2 ... #Allergy #Immunology
Pediatric Mouth Disorders - Differential Diagnosis Algorithm
Teeth:
 • Teething
Painful - Gastrointestinal:
 • Crohn's Disease
 • Ulcerative
Differential Diagnosis Algorithm ... Inflammation: • Allergic ... Reaction #Mouth ... Differential #Diagnosis #Algorithm ... #Causes #Peds #
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Disorders Testing Algorithm ... for secondary causes ... eosinophilia (common causes ... are asthma, allergy ... , drug reaction,