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differential hypersensitivity reactions glomerular hematology management nephrology nephrotic rheumatology table testing vasculitis allergic angioedema champs clinicopathology comparison cryoglobulinemia cryoglobulins definitions
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... glomerulonephritis, type ... 1 (50%-80%), type ... #Low #Complement ... CHAMPS #Mnemonic #diagnosis
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
When the specific allergen ... antigen, leading to complement ... Complement activation ... #Classification ... #Diagnosis #Reactions
Angioedema - Classification Diagnosis and Treatment Types of Angioedema: • Acute allergic angioedema - Usually occurs with
Angioedema - Classification ... Diagnosis and Treatment ... Types of Angioedema ... cell-mediated in > 90% of cases ... #Types #Diagnosis
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
lgE causes mast-cell ... antigens, leading to complement ... they activate complement ... #allergy #table ... #classification
Hypersensitivity: Definitions • Type I - Production of lgE Abs that bind to harmless allergens and
Definitions • Type ... cell surfaces causes ... causes development ... #Types #Classification ... #Diagnosis #Definitions
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Disorders Testing Algorithm ... evaluation or workup ... 1,500 cells/µL Workup ... are asthma, allergy ... #Differential #diagnosis
Major neurocognitive disorders (MNCD): Diagnosis and workup 1) Clinical diagnosis Cognitive impairment + loss of autonomy 2)
workup What type ... Alzheimer - 1st cause ... Dementia - 2nd cause ... Differential #Subtypes #Classification ... #Workup #Diagnosis
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... Labs/Diagnosis: ... • Low serum C4 complement ... #types #classification
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... tract, and often causes ... Urticaria and hypocomplementemia ... against MPO • Complement ... #rheumatology #classification
Type 2 Diabetes - Screening, Diagnosis and Management Algorithm Lifestyle Modifications (Diet and Exercise) -> Start
Type 2 Diabetes ... - Screening, Diagnosis ... and Management Algorithm ... • Secondary Causes ... #DM2 #DMII #Classification
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