17 results
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... glomerulonephritis, type ... 1 (50%-80%), type ... @AnnKumfer #Hypocomplementemia ... #Low #Complement
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Hypersensitivity ... antigen, leading to complement ... Complement activation ... sclerosis #Hypersensitivity ... #Types #Classification
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
of hypersensitivity ... Allergen-specific lgE causes ... antigens, leading to complement ... they activate complement ... allergy #table #classification
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... • Low serum C4 complement ... vasculitis • Hypersensitivity ... #classification
Comprehensive pathogenesis of IgA Nephropathy (i.e Berger’s Disease). 

IgA Nephropathy is the most common cause of
the most common cause ... - What type of Hypersensitivity ... Relationship of complement ... PediatricNephrology #Hypersensitivity
Angioedema - Classification Diagnosis and Treatment
Types of Angioedema:
 • Acute allergic angioedema - Usually occurs with
Angioedema - Classification ... and Treatment Types ... cell-mediated in > 90% of cases ... #Types #Diagnosis ... #Treatment #management
Type 2 Diabetes - Screening, Diagnosis and Management Algorithm
Lifestyle  Modifications (Diet and Exercise) -> Start
Type 2 Diabetes ... Diagnosis and Management ... Algorithm Lifestyle ... • Secondary Causes ... #DMII #Classification
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
Hypersensitivity ... cell surfaces causes ... exposure to allergen causes ... #Hypersensitivity ... #Classification
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... against MPO • Complement ... #rheumatology #classification
Post-Transplantation Lymphoproliferative Disorders (PTLD)
Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
by transplant type ... organ transplant: Type ... Diagnosis and classification ... to 50% of PTLD cases ... oncology #diagnosis #management