10 results
Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
Hypersensitivity ... Penicillin-induced drug reaction ... Dermatitis (ie. reaction ... #Reactions #Types ... #Classification
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
Hypersensitivity ... allergic reaction ... An allergic reaction ... #Hypersensitivity ... #Classification
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
table of types of hypersensitivity ... cell antigens, leading ... to complement activation ... they activate complement ... #classification
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Hypersensitivity ... cellular antigen, leading ... Complement activation ... #Types #Classification ... #Diagnosis #Reactions
Type I Hypersensitivity: Pathogenesis and clinical findings
Definition: Production of lgE Antibodies that bind to harmless allergens
Type I Hypersensitivity ... degranulation, leading ... to an allergic ... reaction. ... Sensitization" to Allergen
Types of hypersensitivity reactions

Type I - lgE-Mediated, Within I Hour (Anaphylaxis)
Type II - IgG or IgM
Types of hypersensitivity ... reactions Type ... #reactions #Types ... #Classification ... #Allergy #Diagnosis
Allergic Bronchopulmonary Aspergillosis (ABPA)
WHAT IS IT?
Hypersensitivity response to Aspergillus fumigatus in the airways
 • Primarily affects
Allergic Bronchopulmonary ... Hypersensitivity ... inflammatory response leading ... Immediate type-skin reaction ... @PulmPEEPs #Allergic
Type II Hypersensitivity: Pathogenesis and clinical findings
Definition: When antigens bind to the body's cell surfaces, forming
Type II Hypersensitivity ... antibody-mediated immune reaction ... activates the complement ... HypersensitivityReaction #Allergy
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... disease, drug reactions ... against MPO • Complement ... #rheumatology #classification
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
immune system, leading ... • Low serum C4 complement ... vasculitis • Hypersensitivity ... diagnosis #types #classification