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diagnosis rheumatology allergy hypersensitivity reactions table comparison erythematosus histiocytosis igg4 langerhans lch lupus pathophysiology sjogrens sle syndrome systemic
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
Hypersensitivity Types ... cellular antigen, leading ... to complement activation ... Complement activation ... #Classification
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Summary table of types ... antigens, leading ... to complement activation ... they activate complement ... allergy #table #classification
IGG-4 RELATED DISEASE WHAT? • A chronic, immune-mediated fibroinflammatory disease with tumefactive infiltration of IgG4+ plasma cells
• Key Features ... • Pancreas: Type ... - ↑ IgE, ↓ complement ... • Classification ... IGG4 #Diagnosis #Management
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Cytopenia: 2% • Hypocomplementemia ... • Can cause TYPE ... IV RTA, TYPE I ... ducts Clinical Features ... Rheumatology #Diagnosis #Management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low complements ... Skin Disease Classification ... Kikuchi disease • Type-I ... Angioimmunoblastic T-cell ... : • Chronic B-cell
Langerhans Cell Histiocytosis (LCH) Granulomatous Lesions comprising langerin-positive histiocytes and an inflammatory infiltrate can arise in virtually
Langerhans Cell ... , a type of dendritic ... various tissues, leading ... : LCH exhibits features ... Histiocytosis #Diagnosis #Management
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