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diagnosis rheumatology differential table allergy hypersensitivity reactions shock vasculitis champs cold comparison criticalcare cryoglobulins diabetes dm2 dmii dry gammopathy hematology
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... Mnemonic C - Cryoglobulinemia ... glomerulonephritis, type ... 1 (50%-80%), type ... #Low #Complement
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Cryoglobulinemia ... immune system, leading ... Types: • Type ... • Low serum C4 complement ... #classification
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
Hypersensitivity Types ... cellular antigen, leading ... to complement activation ... Complement activation ... #Classification
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Summary table of types ... cell antigens, leading ... to complement activation ... they activate complement ... allergy #table #classification
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
ANCA +MPO) • Cryoglobulinemic ... often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... against MPO • Complement ... #rheumatology #classification
Shock Types - Classification State of cellular and tissue hypoxia due to: reduced oxygen delivery, increased oxygen
Shock Types - Classification ... - Most common type ... Hemorrhagic → leading ... water #Shock #Classification ... #management #criticalcare
Shock Classification Shock Definition: State of cellular and tissue hypoxia due to: reduced oxygen delivery, increased oxygen
Shock Classification ... • Most common type ... Hemorrhagic → leading ... #Types #diagnosis ... #management #cold
Type 2 Diabetes - Screening, Diagnosis and Management Algorithm Lifestyle Modifications (Diet and Exercise) -> Start
Type 2 Diabetes ... Diagnosis and Management ... Algorithm Lifestyle ... #algorithm #DM2 ... #DMII #Classification
IGG-4 RELATED DISEASE WHAT? • A chronic, immune-mediated fibroinflammatory disease with tumefactive infiltration of IgG4+ plasma cells
• Pancreas: Type ... - ↑ IgE, ↓ complement ... • Classification ... mimics excluded MANAGEMENT ... IGG4 #Diagnosis #Management
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Cytopenia: 2% • Hypocomplementemia ... • Can cause TYPE ... IV RTA, TYPE I ... Vasculitis: • 7%, Cryoglobulinemia ... Rheumatology #Diagnosis #Management
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