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diagnosis rheumatology causes allergy hypersensitivity vasculitis glomerulonephritis nephrology rpgn table allergic champs clinicopathology comparison criticalcare cryoglobulinemia cryoglobulins definitions dermatology diseases
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... 1 (50%-80%), type ... S - Systemic Lupus ... #Low #Complement ... Mnemonic #diagnosis #differential
Lupus Nephritis Classification Algorithm #Lupus #Nephritis #Classification #Algorithm #diagnosis #differential #types #rheumatology #nephrology #renal
Lupus Nephritis ... Classification Algorithm ... #Classification ... #differential # ... types #rheumatology
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
hypersensitivity reactions ... antigens, leading to complement ... they activate complement ... glomerulonephritis, Systemic lupus ... #table #classification
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Penicillin-induced drug reaction ... • Ex: Systemic Lupus ... Dermatitis (ie. reaction ... Allergy #Allergic #Reactions ... #Types #Classification
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
antigen, leading to complement ... Complement activation ... , and systemic lupus ... #Classification ... Allergy #Diagnosis #Reactions
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
staining): • Low Complement ... Post-strep GN, Lupus ... Idiopathic • Normal Complement ... Glomerulonephritis #Vasculitis #differential ... #diagnosis #algorithm
Hemolysis Classification - Intrinsic and Extrinsic Causes Commentary: Another way to think of immune hemolysis would be
Hemolysis Classification ... hemolytic transfusion reactions ... #Hemolysis #Classification ... Intrinsic #Extrinsic #Differential ... Diagnosis #Causes #Algorithm
Vesiculobullous Skin Rash - Differential Diagnosis Algorithm Vesicles Fragile/EasiIy Ruptured - Intraepidermal blisters, possibly crusts/erosions - Inflammatory
Vesiculobullous Skin Rash - Differential ... Diagnosis Algorithm ... Bullous impetigo - Reaction ... Bullous systemic lupus ... #Diagnosis #Algorithm
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
inflammation Others: • Lupus ... such as systemic lupus ... disease, drug reactions ... against MPO • Complement ... #rheumatology #classification
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Types: • Type ... • Type III Often ... • Low serum C4 complement ... (e.g. systemic lupus ... #classification
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